Her professional interests include psychiatric services, specifically those involving recovery from severe mental illnesses, and housing for chronically homeless populations.We are indebted to our colleagues at the Centers for Disease Control and Prevention in Fort Collins, Colorado, and the 1999 New York City West Nile Virus Outbreak Response Working Group for their contributions. Proxies were used when case-patients could not be interviewed because of poor health, hearing difficulties, or a language barrier. West Nile virus has become endemic in all 48 contiguous United States as well as all Canadian provinces since its discovery in North America in New York City in1999. Most people with this type of West Nile virus disease recover completely, but fatigue and weakness can last for weeks or months.
As WNV continues to establish itself as a national public health concern, these findings reinforce the need for local governments in affected areas to institute widespread public health measures to safeguard against WNV transmission and for persons—especially those above age 65—to take precautions to avoid exposure to mosquitoes and reduce mosquito breeding sites on their properties. Das Virus infiziert hauptsächlich Vögel, kann aber auch auf Menschen, Pferde und andere Säugetiere übergreifen. Anne Labowitz Klee*, Beth Maldin*, Barbara Edwin*, Iqbal Poshni*, Farzad Mostashari*, Annie D. Fine*, Marcelle Layton*, and Denis Nash*†Centers for Disease Control and Prevention. West Nile virus is a mosquito-borne flavivirus originally isolated in 1937 from the blood of a febrile woman in the West Nile province of Uganda. Das West-Nil-Virus (wissenschaftlich West Nile virus, WNV) ist ein seit 1937 bekanntes, behülltes RNA-Virus des Typs ss(+)-RNA aus der Familie Flaviviridae, das sowohl in tropischen als auch in gemäßigten Gebieten vorkommt. Thirty-eight (90.5%) of the 42 case-patients completed the first interview (6 months postonset), 35 (83.3%) participated in the second interview (12 months postonset), and 36 (85.7%) participated in the third interview (18 months postonset). West Nile virus can cause West Nile fever, a mild form of the illness, which can include fever, headache, body aches, swollen lymph nodes or a rash. Some people develop a … All cognitive symptoms were present in case-patients at intervals extending up to 18 months after acute illness (The mean domain-specific health status score was significantly lower at 12 months compared with baseline for all three domains (data not shown). In 2012, the highest numbers of West Nile Virus (WNV) cases were reported by the Center for Disease Control since 2003. Eighteen months after illness, 30% of case-patients reported needing assistance with activities of daily living, mostly those requiring increased strength. We are especially grateful to the recovering patients who graciously agreed to participate in this investigation to further our understanding of the long-term sequelae of West Nile virus infection.Please use the form below to submit correspondence to the authors or contact them at the following address: A symptom was counted as being present if it was experienced sometimes or often. The virus is widely distributed in Africa, Europe, Australia, and Asia, and, since 1999, it has spread rapidly throughout the western hemisphere, including the USA, Canada, Mexico, and the Caribbean and into parts of Central and South America. Efforts aimed at preventing WNV infection should focus on elderly populations who are at increased risk for neurologic manifestations and more likely to experience long-term sequelae of WNV illness. Functional recovery from neuroinvasive west nile virus: A tale of two courses.
These sequelae may be attributable to the patients’ WNV infection, to the more general effects of serious illness and hospitalization, or to the aging process itself; regardless, WNV causes severe neurologic illness and might be associated with lasting sequelae in persons >65 years.Baseline clinical status was not significantly associated with recovery at 12 months (RR = 1.4, 95% CI 0.58–3.3), even after adjusting for age (adjusted RR = 1.3, 95% CI 0.70–2.5). CSF suggestive of viral infection was defined as a negative bacterial stain and culture, with elevated leukocyte count (Blood specimens were obtained at 6-month intervals starting at 6 months through 18 months after illness onset, until WNV-specific IgM, indicative of recent infection, was undetectable. Data were analyzed by using the SPSS System for Windows, version 10.0 and SAS Version 8 (SAS Institute, Cary, NC).Verbal consent was obtained from participants during telephone interviews, and written consent was obtained before follow-up blood specimen collection. RRs were adjusted by using the method of Mantel and Haenszel. Die WNV-Infektion beim Menschen verläuft in der überwiegenden Zahl der Fälle (ca. West Nile virus can cause West Nile fever, a mild form of the illness, which can include fever, headache, body aches, swollen lymph nodes or a rash. Younger age at infection was the only significant predictor of recovery. Follow-up interviews were conducted and blood was collected at approximately 6-month intervals from laboratory confirmed case-patients whose WNV infections were diagnosed in 1999.
Persons with a 12-month composite score >85% of baseline for a given health status domain were considered to be recovered in that domain. Entering your postal code will help us provide news or event updates for your area. She is the clinical director of the Psychosocial Rehabilitation Fellowship Program at the Errera Community Care Center of VA. The study underwent human subjects review and was approved by institutional review boards of both the New York City Department of Health and Centers for Disease Control and Prevention.The prevalence of cognitive symptoms was higher 1 year after illness compared with baseline for all cognitive outcomes.
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